2027-28 San Francisco 49ers Schedule
The San Francisco 49ers upcoming football game schedule for 2027 NFL season and 2028 NFL playoffs rounds are set according to the official sources and subject to change. Below is a full list of Niners’ opponents with time, date, location, TV and predictions for each of the games.
Where do San Francisco 49ers play their home game?
49ers play their home game at Levi’s Stadium, Santa Clara, CA.
2027-28 San Francisco 49ers Regular Season
| Week | Date | Opponents | Time (ET) | Prediction |
| 1 | TBD | at Pittsburgh Steelers | TBD | |
| 2 | TBD | at Los Angeles Rams | TBD | |
| 3 | TBD | New York Giants | TBD | |
| 4 | TBD | Arizona Cardinals | TBD | |
| 5 | TBD | Dallas Cowboys | TBD | |
| 6 | TBD | at Cleveland Browns | TBD | |
| 7 | TBD | at Minnesota Vikings | TBD | |
| 8 | TBD | Cincinnati Bengals | TBD | |
| 9 | TBD | BYE | TBD | |
| 10 | TBD | at Jacksonville Jaguars | TBD | |
| 11 | TBD | Tampa Bay Buccaneers | TBD | |
| 12 | TBD | at Seattle Seahawks | TBD | |
| 13 | TBD | at Philadelphia Eagles | TBD | |
| 14 | TBD | Seattle Seahawks | TBD | |
| 15 | TBD | at Arizona Cardinals | TBD | |
| 16 | TBD | Los Angeles Rams | TBD | |
| 17 | TBD | at Washington Commanders | TBD | |
| 18 | TBD | TBD | TBD |