NFL Week 17 Picks and Predictions (2025)

NFL Week 17 arrives with massive playoff implications across both conferences. With division races tightening and Wild Card spots still up for grabs, every snap matters. From the Christmas Day tripleheader to a loaded Sunday slate and a Monday night finale, this week offers high-stakes football and betting value. Below are game-by-game Week 17 picks and score predictions, based on current DraftKings lines, matchups, and recent form.

Thursday, December 25, 2025 (Christmas Day)

Dallas Cowboys @ Washington Commanders

• Pick: Cowboys -6.5
• Prediction: Cowboys 31, Commanders 23
• Dallas’ offense has been more consistent, and Washington struggles to keep pace against playoff-caliber teams. Expect Dallas to control the game tempo.

Detroit Lions @ Minnesota Vikings

• Pick: Lions -6
• Prediction: Lions 27, Vikings 20
• Detroit’s balance on both sides of the ball gives them the edge indoors. Minnesota keeps it close but falls late.

Denver Broncos @ Kansas City Chiefs

• Pick: Broncos -12.5
• Prediction: Broncos 24, Chiefs 13
• A low total reflects offensive concerns for Kansas City. Denver’s defense and run game should dominate time of possession.

Saturday, December 27, 2025

Houston Texans @ Los Angeles Chargers

• Pick: Chargers -2.5
• Prediction: Chargers 23, Texans 20
• This one feels tight throughout, but home-field advantage and late execution favor Los Angeles.

Baltimore Ravens @ Green Bay Packers

• Pick: Packers -2.5
• Prediction: Packers 24, Ravens 21
• Cold conditions at Lambeau Field play into Green Bay’s hands. Expect a physical, close finish.

Sunday, December 28, 2025

Arizona Cardinals @ Cincinnati Bengals

• Pick: Bengals -7
• Prediction: Bengals 34, Cardinals 24
• Cincinnati’s offense should thrive in a high-total game, especially at home.

Pittsburgh Steelers @ Cleveland Browns

• Pick: Steelers -3.5
• Prediction: Steelers 20, Browns 16
• With a low over/under, points will be hard to find. Pittsburgh’s defense makes the difference.

New Orleans Saints @ Tennessee Titans

• Pick: Saints -2.5
• Prediction: Saints 23, Titans 19
• New Orleans’ efficiency on offense gives them the edge in a grind-it-out matchup.

Jacksonville Jaguars @ Indianapolis Colts

• Pick: Jaguars -6.5
• Prediction: Jaguars 30, Colts 21
• Jacksonville’s playmakers should exploit mismatches, especially in the second half.

Tampa Bay Buccaneers @ Miami Dolphins

• Pick: Buccaneers -5.5
• Prediction: Buccaneers 28, Dolphins 22
• Tampa Bay’s defense limits explosive plays and helps secure a road win.

New England Patriots @ New York Jets

• Pick: Patriots -13.5
• Prediction: Patriots 31, Jets 14
• New England is heavily favored and should cruise if they avoid turnovers.

Seattle Seahawks @ Carolina Panthers

• Pick: Seahawks -7.5
• Prediction: Seahawks 27, Panthers 17
• Seattle’s offense finds success against a Carolina defense that’s struggled all season.

New York Giants @ Las Vegas Raiders

• Pick: Raiders -1.5
• Prediction: Raiders 24, Giants 21
• This matchup feels like a coin flip, but Las Vegas gets the nod at home.

Philadelphia Eagles @ Buffalo Bills

• Pick: Bills -1.5
• Prediction: Bills 26, Eagles 24
• One of Week 17’s best games. Buffalo’s home crowd provides the slight edge in a playoff-style battle.

Chicago Bears @ San Francisco 49ers

• Pick: 49ers -3
• Prediction: 49ers 30, Bears 27
• Expect fireworks in a high-total Sunday night game, with San Francisco making the key late stop.

Monday, December 29, 2025

Los Angeles Rams @ Atlanta Falcons

• Pick: Rams -7.5
• Prediction: Rams 31, Falcons 21
• The Rams’ offensive firepower should be too much for Atlanta under the lights.

Final Thoughts

Week 17 is all about urgency. Teams fighting for playoff positioning tend to lean on experience, defense, and coaching stability-key factors reflected in this week’s spreads. As always, late-season injuries and motivation matter just as much as talent, so monitor line movement closely. This slate delivers value, drama, and postseason energy-exactly what NFL fans wait all year for.