2025 Chiefs vs Commanders Predictions

The Kansas City Chiefs and the Washington Commanders are set to face off in Week 8 of the 2025 NFL season on Monday Night Football. The Chiefs will be heavy favorites at home, while Washington continues to struggle with key injuries. Still, the Commanders will look to overcome their challenges, so let’s take a closer look at what to expect from this matchup.

Commanders starting quarterback Jayden Daniels is dealing with a hamstring injury, making Marcus Mariota the likely starter. Mariota has thrown for 426 yards and three touchdowns so far this season. Washington’s defense is also affected, as standout pass rusher Dorance Armstrong is battling a knee injury after recording 5.5 sacks this year.

Kansas City enters this game with confidence after back-to-back wins over the Detroit Lions and a dominant 31-0 victory over the Las Vegas Raiders, where Patrick Mahomes threw for 286 yards, Travis Kelce led the receivers with 54 yards, and Isiah Pacheco powered the ground game with 57 rushing yards. The Chiefs look sharp on offense and confident heading into this Week 8 matchup. However, experts believe their defense still needs noticeable improvement.

Kansas City Chiefs vs Washington Commanders

  • Location: Kansas City, Missouri
  • Date: Oct. 27, 2025
  • Time: 8:15 p.m. ET
  • TV: ESPN

Kansas City vs Washington Predictions

Oddsmakers see this matchup leaning heavily toward Kansas City. The Chiefs enter as 12.5-point favorites as they look to continue their winning momentum, while Washington aims to pull off a massive road upset. The total is listed at 48 points, signaling expectations for a solid scoring night.

  • Spread: Chiefs -12.5 (-110), Commanders +12.5 (-110)
  • Moneyline: Chiefs -800, Commanders +550
  • Over/Under: 48 (O: -110, U: -110)

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