2025 NFL Week 5 Schedule: Picks and Predictions
The League is scheduled to kick off 2025 NFL Week 5 with a TNF game on Thursday, October 2 between the San Francisco 49ers at LA Rams start at 8:15 pm live on Prime Video. Here is your NFL Week 5 full schedule with , date, time, TV channel, location, picks and predictions below.
What TV channels will be televised NFL Week 5 games?
Week 5’s TNF game on Amazon Prime Video, Sunday day games on FOX, and CBS TV channels and SNF on NBC, and MNF on ESPN TV channels are set to broadcast the 2025 Week 5 games from Oct 2-6, in the United States. Fans can also stream all the games via cable TV networks.
2025 NFL Week 5 TV Schedule
Thursday, October 2
| Game | Time (ET) | TV/Mobile | Predictions |
| San Francisco at LA Rams | 8:15 PM | Prime Video | TBA |
Sunday, October 5
| Game | Time (ET) | TV/Mobile | Predictions |
| Minnesota vs Cleveland (in London, England) | 9:30 AM | NFLN | TBA |
| Houston at Baltimore | 1:00 PM | CBS | TBA |
| Miami at Carolina | 1:00 PM | FOX | TBA |
| Las Vegas at Indianapolis | 1:00 PM | FOX | TBA |
| NY Giants at New Orleans | 1:00 PM | CBS | TBA |
| Dallas at NY Jets | 1:00 PM | FOX | TBA |
| Denver at Philadelphia | 1:00 PM | CBS | TBA |
| Tennessee at Arizona | 4:05 PM | CBS | TBA |
| Tampa Bay at Seattle | 4:05 PM | CBS | TBA |
| Detroit at Cincinnati | 4:25 PM | FOX | TBA |
| Washington at LA Chargers | 4:25 PM | FOX | TBA |
| New England at Buffalo | 8:20 PM | NBC | TBA |
Monday, October 6
| Game | Time (ET) | TV/Mobile | Predictions |
| Kansas City at Jacksonville | 8:15 PM | ESPN/ABC | TBA |