2025 NFL Week 4 Schedule: Picks and Predictions
The League is scheduled to kick off 2025 NFL Week 4 with a TNF game on Thursday, September 25 between the Seattle Seahawks at Arizona Cardinals start at 8:15 pm live on Prime Video. Here is your NFL Week 9 full schedule with , date, time, TV channel, location, picks and predictions below.
What TV channels will be televised NFL Week 4 games?
Week 4’s TNF game on Amazon Prime Video, Sunday day games on FOX, and CBS TV channels and SNF on NBC, and MNF on ESPN TV channels are set to broadcast the 2025 Week 4 games from Sep 25-29, in the United States. Fans can also stream all the games via cable TV networks.
2025 NFL Week 4 TV Schedule
Thursday, September 25
| Game | Time (ET) | TV/Mobile | Predictions |
| Seattle at Arizona | 8:15 PM | Prime Video | Ari (28-26) |
Sunday, September 28
| Game | Time (ET) | TV/Mobile | Predictions |
| Minnesota vs Pittsburgh (in Dublin, Ireland) | 9:30 AM | NFLN | PIT (27-24) |
| Washington at Atlanta | 1:00 PM | CBS | ATL (25-22) |
| New Orleans at Buffalo | 1:00 PM | CBS | BUF (42-13) |
| Cleveland at Detroit | 1:00 PM | FOX | DET (38-13) |
| Tennessee at Houston | 1:00 PM | CBS | Hou (28-16) |
| Carolina at New England | 1:00 PM | FOX | NE (25-27) |
| LA Chargers at NY Giants | 1:00 PM | CBS | LAC (28-18) |
| Philadelphia at Tampa Bay | 1:00 PM | FOX | TB (25-23) |
| Indianapolis at LA Rams | 4:05 PM | FOX | LAR (28-24) |
| Jacksonville at San Francisco | 4:05 PM | FOX | SF (26-17) |
| Baltimore at Kansas City | 4:25 PM | CBS | KC (30-28) |
| Chicago at Las Vegas | 4:25 PM | CBS | LV (20-18) |
| Green Bay at Dallas | 8:20 PM | NBC | DAL (30-29) |
Monday, September 29
| Game | Time (ET) | TV/Mobile | Predictions |
| NY Jets at Miami | 7:15 PM | ESPN | MIA (22-20) |
| Cincinnati at Denver | 8:15 PM | ABC | DEN (27-25) |