2025 NFL Week 4 Schedule: Picks and Predictions

The League is scheduled to kick off 2025 NFL Week 4 with a TNF game on Thursday, September 25 between the Seattle Seahawks at Arizona Cardinals start at 8:15 pm live on Prime Video. Here is your NFL Week 9 full schedule with , date, time, TV channel, location, picks and predictions below.

What TV channels will be televised NFL Week 4 games?

Week 4’s TNF game on Amazon Prime Video, Sunday day games on FOX, and CBS TV channels and SNF on NBC, and MNF on ESPN TV channels are set to broadcast the 2025 Week 4 games from Sep 25-29, in the United States. Fans can also stream all the games via cable TV networks.

2025 NFL Week 4 TV Schedule

Thursday, September 25

GameTime (ET)TV/MobilePredictions
Seattle at Arizona8:15 PMPrime VideoAri (28-26)

Sunday, September 28

GameTime (ET)TV/MobilePredictions
Minnesota vs Pittsburgh (in Dublin, Ireland)9:30 AMNFLNPIT (27-24)
Washington at Atlanta1:00 PMCBSATL (25-22)
New Orleans at Buffalo1:00 PMCBSBUF (42-13)
Cleveland at Detroit1:00 PMFOXDET (38-13)
Tennessee at Houston1:00 PMCBSHou (28-16)
Carolina at New England1:00 PMFOXNE (25-27)
LA Chargers at NY Giants1:00 PMCBSLAC (28-18)
Philadelphia at Tampa Bay1:00 PMFOXTB (25-23)
Indianapolis at LA Rams4:05 PMFOXLAR (28-24)
Jacksonville at San Francisco4:05 PMFOXSF (26-17)
Baltimore at Kansas City4:25 PMCBSKC (30-28)
Chicago at Las Vegas4:25 PMCBSLV (20-18)
Green Bay at Dallas8:20 PMNBCDAL (30-29)

Monday, September 29

GameTime (ET)TV/MobilePredictions
NY Jets at Miami7:15 PMESPNMIA (22-20)
Cincinnati at Denver8:15 PMABCDEN (27-25)

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